Dr. Laura Alonso Chosen for Fellowship in Prestigious Executive Leadership Program

June 23, 2022

Dr. Laura Alonso has been selected to be a fellow of the Hedwig van Ameringen Executive Leadership in Academic Medicine (ELAM) Program at Drexel University College of Medicine. The competitive, year-long fellowship is the only program in North America dedicated to preparing women for senior leadership roles in academic science institutions.

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Team co-led by Dr. Marcus Goncalves receives $25m Cancer Grand Challenges funding

June 16, 2022

Representing a total investment of $100m funded through the partnership between Cancer Research UK and the National Cancer Institute in the US, the Cancer Grand Challenges community unites more than 700 researchers and advocates to take on 10 challenges, across 11 teams and 10 countries. The CANCAN team will take on the Cachexia challenge. Led by Eileen White (Rutgers Cancer Institute of New Jersey), Marcus DaSilva Goncalves (Weill Cornell Medicine) and Tobias Janowitz (Cold Spring Harbor Laboratory), the team will develop a deeper understanding of this debilitating wasting condition often in the later stages of cancer and identify urgently needed therapies.  

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Tirzepatide powers ‘unprecedented’ weight loss in SURMOUNT-1

June 6, 2022

The weight-loss results seen in SURMOUNT-1 “put tirzepatide squarely in the range of weight loss achieved with bariatric surgery,” concluded Metabolic Center member Louis J. Aronne, MD, a coinvestigator on the trial, professor at WCM, director of the Center for Weight Management and Metabolic Clinical Research of Weill Cornell.

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Rachel Stahl received the Association of Diabetes Care & Education Specialists Rising Star Award

June 1, 2022

The Association of Diabetes Care & Education Specialists Rising Star Award recognizes a diabetes care and education specialist who has less than five years of diabetes care and education. experience and has demonstrated leadership and commitment in their practice.

Dr. Shannon Reilly received a Research Assistance for Primary Parents Award for 2022

May 31, 2022

The Research Assistance for Primary Parents Initiative provides technical support to exceptional faculty members, both male and female, who are primary caregivers for an infant or child. Its goal is to help recipients advance their research projects while also negotiating childcare responsibilities. 

Dr. Shahin Rafii inducted into Association of American Physicians

April 11, 2022

Three distinguished Weill Cornell Medicine physician-scientists, Dr. Joseph J. Fins, Dr. Rainu Kaushal and Dr. Shahin Rafii, have been elected to the esteemed Association of American Physicians (AAP).

Regarded as one of the top honors in the field of health and medicine, election to the AAP recognizes physician-scientists exhibiting excellence in the pursuit of medical knowledge and advancing basic or translational science discoveries and their use in clinical medicine.

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Are COVID-19-Linked Arrhythmias Caused by Viral Damage to the Heart’s Pacemaker Cells?

April 1, 2022

The SARS-CoV-2 virus can infect specialized pacemaker cells that maintain the heart’s rhythmic beat, setting off a self-destruction process within the cells, according to a preclinical study co-led by Metabolic Center member Dr. Shuibing Chen at Weill Cornell Medicine, NewYork-Presbyterian and NYU Grossman School of Medicine. The findings offer a possible explanation for the heart arrhythmias that are commonly observed in patients with SARS-CoV-2 infection. In the study, reported March 8 in Circulation Research, the researchers used an animal model as well as human stem cell-derived pacemaker cells to show that SARS-CoV-2 can readily infect pacemaker cells and trigger a process called ferroptosis, in which the cells self-destruct but also produce reactive oxygen molecules that can impact nearby cells.

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New York Post: “New research shows higher risk of developing diabetes after COVID infection"

March 22, 2022

Metabolic Center faculty member Dr. Shuibing Chen was featured in a New York Post article titled “New research shows higher risk of developing diabetes after COVID infection.” 

There are several possible biological reasons why a diabetes diagnosis might follow a COVID-19 infection. “The beta cells lost their cell identity and turned into a different type of cell,” says Shuibing Chen, director of the diabetes program at Weill Cornell Medicine in Manhattan, who led the study. Dr. Chen says COVID-19 infection appears to be triggering a new type of diabetes that isn’t Type 1 or Type 2. Dr. Chen says her team is studying treatments specifically for COVID-19 patients newly diagnosed with diabetes to see whether they can block the process by which the cells might change.

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Researchers Awarded Grant to Study New Method of Islet Transplantation

January 5, 2022

Members of the Weill Center for Metabolic Health, Dr. Rebecca Craig-SchapiroDr. Shahin Rafii, and Dr. Qiao Zhou, have received a two-year $500,000 grant from JDRF to evaluate an innovative approach to islet cell transplantation, an experimental treatment for difficult-to-control type 1 diabetes. The research will be conducted in mouse models of this disease.

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Faculty Honors and Awards

December 30, 2021

Metabolic Center member Dr. Louis Aronne, the Sanford I. Weill Professor of Metabolic Research and a professor of clinical medicine, has been awarded the Clinician of the Year Award by the Clinical Management of Obesity Section of The Obesity Society. The Clinician of the Year Award signifies excellence in the practice of obesity medicine and distinguishes a physician as having achieved a high level of competency and understanding in obesity care.

Researchers Identify Significant Differences in Tumor Characteristics Between Younger and Older Cancer Patients

December 7, 2021

Investigators led by our Metabolic Center member Dr. Olivier Elemento have identified significant differences in the molecular characteristics of tumors from younger and older cancer patients across several cancer types. Their research, published Dec. 7 in Cell Reports, suggests that cancer treatment could potentially be tailored by age. The study also identified pre-existing drugs that could target mutations predominantly found in younger cancer patients—promising candidates for future clinical research.

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Protein Variant Identified that Renders Chemotherapy Ineffective in Gastric Cancer

December 6, 2021

A new protein variant underlies the ability of gastric cancers to resist an otherwise effective family of chemotherapy drugs, according to a study by a multidisciplinary team including co-senior author Dr. Olivier Elemento, a member of the Weill Center for Metabolic Health. The results suggest a treatment strategy that could improve the prognoses of many patients with cancer.

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Researchers Discover the Role the Gene SATB2 Plays in the Colon Lining

October 28, 2021

Loss of the gene SATB2 contributes to changes in stem cells that typically develop into the inner lining of the colon, or large intestine, transforming them into a cell type that normally lines a portion of the small intestine called the ileum, according to new preclinical research led by our Metabolic Center member, Dr. Joe Zhou, in a study published Sept. 27 in Cell Stem Cell

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Dr. Kristy Brown was just appointed Co-Editor-in Chief of the journal Endocrine and Metabolic Science. This is a broad-scope, open access journal accepting basic, translational and clinical original articles, reviews, clinical trials and case reports on all aspects of endocrinology and metabolism. Dr. Brown looks forward to building this new journal that focusses on many exciting areas of research relevant to our faculty, including obesity and...

COVID-19 may bring high risks of severe disease and death in many patients by disrupting key metabolic signals and thereby triggering hyperglycemia, according to a new study from researchers at Weill Cornell Medicine and NewYork-Presbyterian. 

In the ...

On September 22, 2021, the Joan and Sanford I. Weill Center for Metabolic Health officially opened with introductory comments by Dr. Laura Alonso, the Center’s Director and Chief of the Division of Endocrinology, Metabolism and Diabetes, Dr. Tony Hollenberg, Chair, Weill Department of Medicine, and Dean Augustine Choi, Dean of Weill Cornell Medicine. Also in attendance were Dr. Lou Aronne, Director of the Comprehensive Weight Control Center, and a vaccinated, masked and socially distanced...

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