Selected Publications From Metabolic Center Members Sept-Dec 2021

Taylor, S. R. et al. and Goncalves, M. D. Dietary fructose improves intestinal cell survival and nutrient absorption. Nature 597, 263-267 (2021).

Reiterer, M. et al. and Lo, J. C. Hyperglycemia in acute COVID-19 is characterized by insulin resistance and adipose tissue infectivity by SARS-CoV-2. Cell Metab 33, 2484 (2021). 

Aronson, B. E. et al. and Apostolou, E. A bipartite element with allele-specific functions safeguards DNA methylation imprints at the Dlk1-Dio3 locus. Dev Cell 56, 3052-3065 e3055 (2021).

Gomez-Salinero, J. M., Itkin, T. & Rafii, S. Developmental angiocrine diversification of endothelial cells for organotypic regeneration. Dev Cell 56, 3042-3051 (2021).

Duan, X. et al. and and Chen, S. An airway organoid-based screen identifies a role for the HIF1alpha-glycolysis axis in SARS-CoV-2 infection. Cell Rep 37, 109920 (2021).

Shah, Y. et al. and Elemento, O. Pan-cancer analysis reveals molecular patterns associated with age. Cell Rep 37, 110100 (2021).

Yang, L. et al. and Chen, S. Cardiomyocytes recruit monocytes upon SARS-CoV-2 infection by secreting CCL2. Stem Cell Reports 16, 2274-2288 (2021).

Sharma, R. B., Landa-Galvan, H. V. & Alonso, L. C. Living Dangerously: Protective and Harmful ER Stress Responses in Pancreatic beta-Cells. Diabetes 70, 2431-2443 (2021).

Goyal, P. et al. and Safford, M. M. Clinical Characteristics and Outcomes of Adults With a History of Heart Failure Hospitalized for COVID-19. Circ Heart Fail 14, e008354 (2021).

Pipalia, N. H. et al. and Maxfield, F. R. HSP90 inhibitors reduce cholesterol storage in Niemann-Pick type C1 mutant fibroblasts. J Lipid Res 62, 100114 (2021).

Tang, X. H. et al. and Gudas, L. J. A retinoic acid receptor beta2 agonist attenuates transcriptome and metabolome changes underlying nonalcohol-associated fatty liver disease. J Biol Chem 297, 101331 (2021).

Baquero, J., Tang, X. H., Scognamiglio, T. & Gudas, L. J. EZH2 knockout in oral cavity basal epithelia causes more invasive squamous cell carcinomas. Carcinogenesis 42, 1485-1495 (2021).

Kolin, D. A., Kulm, S. & Elemento, O. Prediction of primary venous thromboembolism based on clinical and genetic factors within the U.K. Biobank. Sci Rep 11, 21340 (2021).

Snyder, J. T., Darko, C., Sharma, R. B. & Alonso, L. C. Endoplasmic Reticulum Stress Induced Proliferation Remains Intact in Aging Mouse beta-Cells. Front Endocrinol (Lausanne) 12, 734079 (2021).

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